Assessment of the symmetry of stem-cell mitoses.
نویسنده
چکیده
A model of Paneth-cell renewal in the small intestinal epithelium is used to estimate the probability that epithelial stem-cell mitoses are symmetric in the sense that they produce two cells of the same type. I found that counts of the number of Paneth cells per crypt (Paneth cells are terminally differentiated cells derived from small intestinal epithelial stem cells) support a model in which most, if not all, stem-cell mitoses are symmetric.
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ورودعنوان ژورنال:
- Biophysical journal
دوره 48 1 شماره
صفحات -
تاریخ انتشار 1985